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Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulinμ heavy-chain transgenic mice

Min ZHANG,Xueqian CHENG,Dan CHU,Jingwen LIANG,Yi SUN,Li MA,Beilei XU,Min ZHENG,Meili WANG,Liming REN,Xiaoxiang HU,Qingyong MENG,Ran ZHANG,Ying GUO,Yunping DAI,Robert AITKEN,Ning LI,Yaofeng ZHAO

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 2,   Pages 158-173 doi: 10.15302/J-FASE-2014015

Abstract: In this study, we introduced the bovine immunoglobulin μ heavy-chain gene (the orphaned gene on BTA11Bovine IgM was highly expressed in selected transgenic lines, and it largely inhibited rearrangementsof the endogenous immunoglobulin heavy chain (IgH) genes in these lines.The forced expression of bovine IgM resulted in reduced numbers of pro- and pre-B cells but increasedBovine IgM-expressing B cells can migrate from the bone marrow to the spleen, but most of the cells are

Keywords： bovine Ig μ heavy-chain     transgenic mice     B cell development     allelic exclusion     immune response     Ig repertoire    

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A comprehensive analysis of immunoglobulin heavy chain genes in the Bactrian camel (

Zuoxiang LIANG,Tao WANG,Yi SUN,Wenlong YANG,Zhihong LIU,Jing FEI,Ying GUO,Qingwei MA,Qingjie PAN,Liming REN

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 3,   Pages 249-259 doi: 10.15302/J-FASE-2015056

Abstract: Heavy chain only antibodies (HCAbs) represent a rare type of antibody that is devoid of light chainstranscript data and genome sequences, we conducted a comprehensive analysis of Bactrian camel immunoglobulin heavychain genes.

Keywords： Bactrian camel     heavy-chain antibodies     VHH     γ3    

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Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Frontiers of Medicine   Pages 957-971 doi: 10.1007/s11684-023-0988-8

Abstract: Dynein axonemal heavy chain 10 (DNAH10) encodes a subunit of the inner arm dynein heavy chain

Keywords： DNAH10     mice     motile cilia     mutation     primary ciliary dyskinesia    

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of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composed of the human heavychain and the rat light chain

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 584-595 doi: 10.1007/s11684-021-0844-7

Abstract: Plasmids containing human FVIII heavy chain (hHC), human light chain (hLC), and rat light chain (rLC)

Keywords： hemophilia A     adeno-associated virus (AAV)     human/rat hybrid factor VIII     gene therapy     dual chain strategy    

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The past, present and future of bovine pluripotent stem cells: a brief overview

Xiuchun TIAN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 3-7 doi: 10.15302/J-FASE-2018247

Abstract:

Although the pursuit of bovine embryonic stem cells started more than 26 years ago for the purposecircuitry across mammalian species may be the main objective for studying pluripotent stem cells in the bovine

Keywords： bovine     embryonic     induced     pluripotent stem cells    

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Development of the expressed immunoglobulin μ chain repertoire during maturation of mice B cells

Jingwen LIANG,Yingfeng LUO,Yi SUN,Meng LEI,Bing ZHANG,Songnian HU,Yaofeng ZHAO

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 3,   Pages 201-213 doi: 10.15302/J-FASE-2014017

Abstract: To gain insight into the shift of the immunoglobulin heavy (IgH) chain repertoire during B cell development, we undertook large scale Ig μ chain repertoire analysis of pre-B, immature B and spleen B cell populationsAll these data indicated that the expressed Ig μ chain repertoire, especially the repertoire of CDRH3

Keywords： repertoire     complementarity determining region 3 of the IgH chain (CDRH3)     immunoglobulin     heavy chain     variable    

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Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 33-41 doi: 10.15302/J-FASE-2018228

Abstract:

Female infertility represents a major challenge for improving the production efficiency in the dairy industry. Historically, fertility has declined whereas milk yield has increased tremendously due to intensive genetic selection. evidence reveals about 60% pregnancy loss takes place during the first month following fertilization. Meanwhile, early embryo development is significant for somatic cell nuclear transfer in cattle as a large proportion of cloned embryos fail to develop beyond peri-implantation stage. Oocyte quality is of utmost importance for the early embryo to develop to term for both fertilized and cloned embryos. Epigenetic reprogramming is a key process occurring after fertilization and critical roles of epigenetic modifiers during preimplantation development are now clear. Incomplete epigenetic reprogramming is believed to be a major limitation to cloning efficiency. Treatment of cloned embryos with epigenetic modifying drugs (e.g., Trichostatin A) could greatly improve cloning efficiency in both mice and cattle. Recently, the rapid progress in high-throughput sequencing technologies has enabled detailed deciphering of the molecular mechanisms underlying these events. The robust efficiency of genomic editing tools also presents an alternative approach to the functional annotation of genes critical to early development.

Keywords： bovine cloning     embryo development     somatic cell nuclear transfer     X-inactive specific transcript    

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Importance of Viral Disease in Dairy Cow Fertility Review

D. Claire Wathes, Chike F. Oguejiofor, Carole Thomas, Zhangrui Cheng

Engineering 2020, Volume 6, Issue 1,   Pages 26-33 doi: 10.1016/j.eng.2019.07.020

Abstract: Acute infection with non-cytopathic bovine viral diarrhea virus (BVDV) in mid-gestation increases abortionBovine herpesvirus (BHV)-1 is most common in pre-pubertal heifers, and can slow their growth, delay breeding

Keywords： Bovine viral diarrhea virus     Bovine herpesvirus-1     Bovine herpesvirus-4     Schmallenberg virus     Bluetongue    

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Structural prediction of porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine

Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 1,   Pages 65-71 doi: 10.15302/J-FASE-2016086

Abstract: Previous studies have shown that a pSn V-set Ig-like domain is significant in PRRSV infection.In this study, we successfully cloned, expressed and purified the pSn V-set Ig-like domain in S2 cells

Keywords： PRRSV     porcine sialoadhesin     V-set Ig-like domain     Drosophila S2 cell     crystallization    

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Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling

Xiaorong Meng, Shanshan Huo, Lei Wang, Xudong Wang, Yongtao Lv, Weiting Tang, Rui Miao, Danxi Huang

Frontiers of Environmental Science & Engineering 2017, Volume 11, Issue 2, doi: 10.1007/s11783-017-0907-9

Abstract: The effects of PES membrane interfacial electrokinetic property on the bovine serum albumin (BSA) membrane

Keywords： Charged PES UF membrane     BSA     Electrokinetic characterization     Adhesion force     Jump distance    

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Co-pyrolysis of sludge and kaolin/zeolite in a rotary kiln: Analysis of stabilizing heavy metals

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 7, doi: 10.1007/s11783-021-1488-1

Abstract:

• Adding kaolin/zeolite promotes the formation of stable heavy metals

Keywords： Co-pyrolysis     Sewage sludge     Heavy metals     Rotary kiln     Immobilization mechanism    

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Effects of sulfur on variations in the chemical speciation of heavy metals from fly ash glass

Frontiers of Environmental Science & Engineering 2023, Volume 17, Issue 10, doi: 10.1007/s11783-023-1728-7

Abstract:

● A higher sulfur content reduced the curing rate of Cr in glass.

Keywords： Dechlorinated fly ash     SO3     Heavy metal     Chemical speciation     Glass solidification    

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Pricing and production strategies in remanufacturing from the perspectives of supply chain: Review and

Frontiers of Engineering Management doi: 10.1007/s42524-023-0251-7

Abstract: literature on pricing and production strategies in remanufacturing from four perspectives of supply chain, namely, government policy, consumer characteristics, relationships among firms, and supply chain structures

Keywords： remanufacturing     reverse and closed-loop supply chain     circular economy    

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ASSESSMENT OF HEAVY METALS IN HYDROCHAR PRODUCED BY HYDROTHERMAL CARBONIZATION OF DAIRY MANURE

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 3,   Pages 437-447 doi: 10.15302/J-FASE-2023507

Abstract:

● Content of heavy metals in hydrochar varies considerably, from 50%

Keywords： heavy metals     dairy manure     hydrochar     hydrothermal carbonization     waste management    

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Modeling of the resilient supply chain system from a perspective of production design changes

Frontiers of Engineering Management   Pages 96-106 doi: 10.1007/s42524-022-0235-z

Abstract: Building an effective resilient supply chain system (RSCS) is critical and necessary to reduce the riskof supply chain disruptions in unexpected scenarios such as COVID-19 pandemic and trade wars.To overcome the impact of insufficient raw material supply on the supply chain in mass disruption scenariosof the change impact process is presented to evaluate the resilience of both the product and supply chain

Keywords： resilient supply chain     supply chain disruption     domain modeling     product design changes    

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Title Author Date Type Operation

Depletion of conventional mature B cells and compromised specific antibody response in bovine immunoglobulinμ heavy-chain transgenic mice

Min ZHANG,Xueqian CHENG,Dan CHU,Jingwen LIANG,Yi SUN,Li MA,Beilei XU,Min ZHENG,Meili WANG,Liming REN,Xiaoxiang HU,Qingyong MENG,Ran ZHANG,Ying GUO,Yunping DAI,Robert AITKEN,Ning LI,Yaofeng ZHAO

Journal Article

A comprehensive analysis of immunoglobulin heavy chain genes in the Bactrian camel (

Zuoxiang LIANG,Tao WANG,Yi SUN,Wenlong YANG,Zhihong LIU,Jing FEI,Ying GUO,Qingwei MA,Qingjie PAN,Liming REN

Journal Article

Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Journal Article

of hemorrhagic diathesis in hemophilia A mice by an AAV-delivered hybrid FVIII composed of the human heavychain and the rat light chain

Journal Article

The past, present and future of bovine pluripotent stem cells: a brief overview

Xiuchun TIAN

Journal Article

Development of the expressed immunoglobulin μ chain repertoire during maturation of mice B cells

Jingwen LIANG,Yingfeng LUO,Yi SUN,Meng LEI,Bing ZHANG,Songnian HU,Yaofeng ZHAO

Journal Article

Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Journal Article

Importance of Viral Disease in Dairy Cow Fertility

D. Claire Wathes, Chike F. Oguejiofor, Carole Thomas, Zhangrui Cheng

Journal Article

Structural prediction of porcine sialoadhesin V-set Ig-like domain sheds some light on its role in porcine

Jie HOU,Rui LI,Hongfang MA,Songlin QIAO,Gaiping ZHANG

Journal Article

Effect of electrokinetic property of charged polyether sulfone membrane on bovine serum albumin fouling

Xiaorong Meng, Shanshan Huo, Lei Wang, Xudong Wang, Yongtao Lv, Weiting Tang, Rui Miao, Danxi Huang

Journal Article

Co-pyrolysis of sludge and kaolin/zeolite in a rotary kiln: Analysis of stabilizing heavy metals

Journal Article

Effects of sulfur on variations in the chemical speciation of heavy metals from fly ash glass

Journal Article

Pricing and production strategies in remanufacturing from the perspectives of supply chain: Review and

Journal Article

ASSESSMENT OF HEAVY METALS IN HYDROCHAR PRODUCED BY HYDROTHERMAL CARBONIZATION OF DAIRY MANURE

Journal Article

Modeling of the resilient supply chain system from a perspective of production design changes

Journal Article